Refusal to nominate speaker derails legislature and raises stakes in London’s dispute with Brussels

Patients put at risk as crisis hits supplies of vital antibiotics, HRT and anti-depressants. / Vital antibiotics, hormone replacement therapy (HRT) and attention deficit hyperactivity disorder (ADHD) drugs are among those in desperately short supply this winter – with the NHS forced to pay over the odds to get drugs into Britain.

The RCGP has formally opposed the UK's exit from the EU and backed a 'people's vote' on Brexit negotiations following a meeting of its governing council.