"Our hefty international influence rested on our history and reputation, buttressed by our membership of the European Union and our close alliance with the United States. Suddenly, we are no longer an irreplaceable bridge between Europe and America. We are now less relevant to them both."

'It is the first time in our long history that any British government has embraced a policy of self-harm, despite their own advisers warning that it will make our nation weaker – and our people poorer.'

In his first public speech since the EU referendum, Sir John Major outlined the realities that he believes both Britain and Europe face in the future at Chatham House.