Patients put at risk as crisis hits supplies of vital antibiotics, HRT and anti-depressants. / Vital antibiotics, hormone replacement therapy (HRT) and attention deficit hyperactivity disorder (ADHD) drugs are among those in desperately short supply this winter – with the NHS forced to pay over the odds to get drugs into Britain.

Those on the frontline are caught between political uncertainty and a scared and sometimes angry public.

Health leaders have written to Boris Johnson issuing new warnings on the impact of a no-deal Brexit.