Patients put at risk as crisis hits supplies of vital antibiotics, HRT and anti-depressants. / Vital antibiotics, hormone replacement therapy (HRT) and attention deficit hyperactivity disorder (ADHD) drugs are among those in desperately short supply this winter – with the NHS forced to pay over the odds to get drugs into Britain.

Those on the frontline are caught between political uncertainty and a scared and sometimes angry public.

The [Yellowhammer] documents themselves outline that there are risks to the supply of medicines - but do not set out the detail of how those risks have been mitigated, and what doctors and patients should do to plan for the possibility.

Health leaders have written to Boris Johnson issuing new warnings on the impact of a no-deal Brexit.